Postinfective Malabsorption: A Sprue Syndrome

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Postinfective malabsorption: a sprue syndrome.

Thirteen cases are described of temporary malabsorption in adults presenting after an episode of apparent infective enteritis. Clinical features included diarrohea, anorexia, and weight loss. Investigations indicated diffuse impairment of function in the small bowel, including the ileum, with well-preserved mucosal morphology in the upper jejunum and a tendency to rapid folate depletion. Sponta...

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The cell population of the upper jejunal mucosa in tropical sprue and postinfective malabsorption.

The cell population of the upper jejunal mucosa has been studied in cases of tropical sprue from the Far East and Middle East, and in similar cases arising in western Europe (;post-infective malabsorption'), and compared with cases of untreated coeliac disease and patients without small bowel disease.Infiltration of the epithelial layer of the upper jejunal mucosa by lymphocytes was found in tr...

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Pteroylglutamic acid malabsorption in tropical sprue.

Pteroylglutamic acid (PGA) absorption was assessed in ten untreated tropical sprue (TS) and eight control subjects utilizing a marker perfusion technique. Physiologic concentrations of the vitamin (25 ng/ml) dissolved in iso-osmotic solutions containing either mannitol of glucose at a concentration of 55.6 mM were perfused on each subject on two consecutive days. A statistically significant dif...

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Hyperoxaluria correlates with fat malabsorption in patients with sprue.

The effect of fat malabsorption on the absorption and renal excretion of dietary oxalate was studied in four patients with sprue and in two patients with dermatitis herpetiformis and sprue-like jejunal histology. Hyperoxaluria was present in all patients with sprue when fat malabsorption was severe. Urinary oxalate excretion decreased in two of the three patients with coeliac sprue when their f...

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Serum cytokine levels in postinfective fatigue syndrome.

To the Editor—[Q1]Previous studies have sought evidence for a role of abnormal cytokine activity in patients with chronic fatigue syndrome and have had conflicting results [1–3]. These ambiguous results may reflect heterogeneity in groups of patients considered to have chronic fatigue syndrome and variations in assay systems. We established postinfective fatigue syndrome as the only well-charac...

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ژورنال

عنوان ژورنال: BMJ

سال: 1973

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5861.265